A woman named Jules flees her apartment. After she runs down the stairs a flash of light happens causing a table and chair to be pulled towards it. As she reaches the sidewalk and looks around a flash occurs behind the camera when Jules is looking towards it. Her eyes become filled with dark grey clouds before another flash occurs and she is flung into the path of a moving car with her head ending up under the wheel. A man in the other apartment, Ian, hears the commotion from his apartment and grabs his phone before taking a picture of Jules’s corpse.

Paul Harris works at a small research facility on the outskirts of Boston. After a weekend tryst with a co-worker leaves him wanting more, his unreciprocated desires gradually mold into an acute infatuation. When Danielle takes interest in a new scientist at the laboratory, Paul’s suppressed resentments and perverse delusions finally become unhinged, triggering a horrific course of events that mercilessly engulf a tortured past and fugitive present.